What's the difference between these two sentence?What's the happiest moment OF your life?What's the happiest moment IN your life?

What's the difference between these two sentence?What's the happiest moment OF your life?What's the happiest moment IN your life?
What's the difference between these two sentence?
What's the happiest moment OF your life?
What's the happiest moment IN your life?

What's the difference between these two sentence?What's the happiest moment OF your life?What's the happiest moment IN your life?
this is the last chance in my life
我这辈子就剩这一个机会了
chocolate is one of life's great pleasures
巧克力真是生活中的一大享受
其实跟wendilvlv的说法是一样的

意思是差不多的。。。。第一个。。。是在你一生中。。。第二个是。。。在你人生中或在你生活中

比较赞同tailuowang的观点
in your life 是你的一生比如 a new stage in your life
但是也有rest of your life生命剩下的部分
如果一定要区别 还是of 生活 in 生命

1. 在你的生活当中，最快乐的时刻是什么？
2. 你一生中最快乐的时刻是什么？